Episode 117 - Dye or Die: Methylene Blue w/Will Heuser

Heavy Lies the Helmet

When discussing methylene blue, management and treatment of methaemoglobinaemia is usually the first indication mentioned. But in this podcast, we challenge you to increase the size of your lense and focus on its benefits in other states (e.g., septic shock). Of course, we could not do this alone, so we invited a Flight Paramedic, Pharmacist, Toxicologist, and Professor to join us. And fortunately for us, they are all the same person.

Tune in as Will Heuser helps us discuss the pathophysiology of distributive shock, the pharmacodynamics and pharmacokinetics of methylene blue related to its effects on endothelial relaxation, and how this simple dye goes beyond that of salvage therapy when a patient has high vasopressor requirements.

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