Episode 9: The Microbiome & Cancer – The Research is PHENOMENAL

PROSPER Natural Cancer CARE with Carla Wrenn

In this episode, Carla explores the ground breaking connection between the microbiome and cancer, emphasising its critical role in cancer development, progression, and treatment responses. Drawing from Hanahan and Weinberg's Hallmarks of Cancer, she highlights the ways in which microbiome research is reshaping our understanding of oncology.

Key Points:

• Microbiome’s Influence on Cancer:
• Modulating the Microbiome for Better Outcomes
• Notable Research Discussed
• Patient-Centred Approach

Carla emphasizes the incredible potential of leveraging microbiome science to improve cancer care, advocating for research-driven, individualised strategies.

Next Episode Preview: Carla dives into strategies for maintaining bone density during and after cancer treatment.

References:

• Hanahan, D. Hallmarks of cancer: new dimensions Cancer Discov. 12 ,31-36 (2022)
• Fulbright LE, Ellermann M, Arthur JC. The microbiome and the hallmarks of cancer. PLoS Pathog. 2017 Sep 21;13(9):e1006480. doi: 10.1371/journal.ppat.1006480. PMID: 28934351; PMCID: PMC5608396.
• Łaniewski P, Ilhan ZE, Herbst-Kralovetz MM. The microbiome and gynaecological cancer development, prevention and therapy. Nat Rev Urol. 2020 Apr;17(4):232-250. doi: 10.1038/s41585-020-0286-z. Epub 2020 Feb 18. PMID: 32071434; PMCID: PMC9977514.
• Andolfi C, Bloodworth JC, Papachristos A, Sweis RF. The Urinary Microbiome and Bladder Cancer: Susceptibility and Immune Responsiveness. Bladder Cancer. 2020 Sep 21;6(3):225-235. doi: 10.3233/BLC-200277. PMID: 33195783; PMCID: PMC7605348
• Dadgar N, Edlukudige Keshava V, Raj MS, Wagner PL. The Influence of the Microbiome on Immunotherapy for Gastroesophageal Cancer. Cancers (Basel). 2023 Sep 5;15(18):4426. doi: 10.3390/cancers15184426. PMID: 37760397; PMCID: PMC10526145.
• Viswanathan S, Parida S, Lingipilli BT, Krishnan R, Podipireddy DR, Muniraj N. Role of Gut Microbiota in Breast Cancer and Drug Resistance. Pathogens. 2023 Mar 16;12(3):468. doi: 10.3390/pathogens12030468. PMID: 36986390; PMCID: PMC10058520
• Bernardo G, Le Noci V, Di Modica M, Montanari E, Triulzi T, Pupa SM, Tagliabue E, Sommariva M, Sfondrini L. The Emerging Role of the Microbiota in Breast Cancer Progression. Cells. 2023 Jul 27;12(15):1945. doi: 10.3390/cells12151945. PMID: 37566024; PMCID: PMC10417285.
• Parida S., Sharma D. The Microbiome-Estrogen Connection and Breast Cancer Risk. Cells. 2019;8:1642. doi: 10.3390/cells8121642
• Rebersek, M. Gut microbiome and its role in colorectal cancer. BMC Cancer 21, 1325 (2021). https://doi.org/10.1186/s12885-021-09054-2

Find PROSPER Natural Cancer CARE on Instagram @prosper.cancer.care or visit www.prospercancercare.co.

For more information or to get in touch, connect with Carla on Instagram @carlawrenn or visit www.carlawrenn.com.

Disclaimer: This podcast is intended to be informational only and represents the opinion of the participants, but not necessarily their workplace. It is not intended to be used as medical advice and does not take the place of advice from a qualified health care practitioner in a clinical setting. Please check with your healthcare practitioner before embarking upon any of the treatments or lifestyle changes discussed.