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#28 Catching black swans – François Montastruc
Manage episode 424661237 series 2749727
Serious and unexpected adverse drug reactions – the ‘black swans’ of pharmacovigilance – can place enormous strain on safety monitoring systems. Drawing examples from the COVID-19 pandemic, François Montastruc from Toulouse University Hospital explains how we can get better at dealing with the unpredictable.
Tune in to find out:
- What Nassim Nicholas Taleb’s ‘black swan’ theory has to do with pharmacovigilance
- What makes an adverse drug reaction a black, white, or grey swan
- Why flexibility and communication are key to patient safety
Want to know more?
Here are the research articles cited in the episode:
- Quality of reporting of adverse events in clinical trials of COVID-19 drugs: systematic review
- Psychiatric disorders and hydroxychloroquine for COVID-19: a VigiBase study
- Hepatic disorders with the use of remdesivir for COVID-19
- Serious bradycardia and remdesivir for COVID-19: a new safety concern
- Oxford-AstraZeneca COVID-19 vaccine-induced cerebral venous thrombosis and thrombocytopaenia: a missed opportunity for a rapid return of experience
- Atypical thrombosis associated with VaxZevria® (AstraZeneca) vaccine: data from the French network of regional pharmacovigilance centres
- Teaching pharmacovigilance to French medical students during the COVID-19 pandemic: interest of distance learning clinical reasoning sessions
If you enjoyed this podcast, check out these related episodes from the Drug Safety Matters archive:
- Reforming pharmacovigilance education
- Lessons in pandemic pharmacovigilance
- Intuition in pharmacovigilance
Join the conversation on social media
Follow us on X, LinkedIn, or Facebook and share your thoughts about the show with the hashtag #DrugSafetyMatters.
Got a story to share?
We’re always looking for new content and interesting people to interview. If you have a great idea for a show, get in touch!
About UMC
Read more about Uppsala Monitoring Centre and how we work to advance medicines safety.
Kapitler
1. #28 Catching black swans – François Montastruc (00:00:00)
2. Intro (00:00:15)
3. Black swan theory (00:01:59)
4. Relevance to pharmacovigilance (00:04:49)
5. Black swan events (00:08:33)
6. White swan events (00:10:51)
7. Grey swan events (00:13:53)
8. The pharmacovigilance 'oiseleur' (00:17:00)
9. Teaching bird-catching (00:19:48)
10. Collaboration is crucial (00:22:49)
11. Outro (00:25:56)
47 episoder
Manage episode 424661237 series 2749727
Serious and unexpected adverse drug reactions – the ‘black swans’ of pharmacovigilance – can place enormous strain on safety monitoring systems. Drawing examples from the COVID-19 pandemic, François Montastruc from Toulouse University Hospital explains how we can get better at dealing with the unpredictable.
Tune in to find out:
- What Nassim Nicholas Taleb’s ‘black swan’ theory has to do with pharmacovigilance
- What makes an adverse drug reaction a black, white, or grey swan
- Why flexibility and communication are key to patient safety
Want to know more?
Here are the research articles cited in the episode:
- Quality of reporting of adverse events in clinical trials of COVID-19 drugs: systematic review
- Psychiatric disorders and hydroxychloroquine for COVID-19: a VigiBase study
- Hepatic disorders with the use of remdesivir for COVID-19
- Serious bradycardia and remdesivir for COVID-19: a new safety concern
- Oxford-AstraZeneca COVID-19 vaccine-induced cerebral venous thrombosis and thrombocytopaenia: a missed opportunity for a rapid return of experience
- Atypical thrombosis associated with VaxZevria® (AstraZeneca) vaccine: data from the French network of regional pharmacovigilance centres
- Teaching pharmacovigilance to French medical students during the COVID-19 pandemic: interest of distance learning clinical reasoning sessions
If you enjoyed this podcast, check out these related episodes from the Drug Safety Matters archive:
- Reforming pharmacovigilance education
- Lessons in pandemic pharmacovigilance
- Intuition in pharmacovigilance
Join the conversation on social media
Follow us on X, LinkedIn, or Facebook and share your thoughts about the show with the hashtag #DrugSafetyMatters.
Got a story to share?
We’re always looking for new content and interesting people to interview. If you have a great idea for a show, get in touch!
About UMC
Read more about Uppsala Monitoring Centre and how we work to advance medicines safety.
Kapitler
1. #28 Catching black swans – François Montastruc (00:00:00)
2. Intro (00:00:15)
3. Black swan theory (00:01:59)
4. Relevance to pharmacovigilance (00:04:49)
5. Black swan events (00:08:33)
6. White swan events (00:10:51)
7. Grey swan events (00:13:53)
8. The pharmacovigilance 'oiseleur' (00:17:00)
9. Teaching bird-catching (00:19:48)
10. Collaboration is crucial (00:22:49)
11. Outro (00:25:56)
47 episoder
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