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Zilebesiran - A New Hypertension Treatment

27:15
 
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Manage episode 379944714 series 2931422
Indhold leveret af CEimpact. Alt podcastindhold inklusive episoder, grafik og podcastbeskrivelser uploades og leveres direkte af CEimpact eller deres podcastplatformspartner. Hvis du mener, at nogen bruger dit ophavsretligt beskyttede værk uden din tilladelse, kan du følge processen beskrevet her https://da.player.fm/legal.

Injectable, long-acting therapy is a new frontier for hypertension management. Join host, Geoff Wall, as he evaluates zilebesiran, a hepatic angiotensinogen blocker for blood pressure control for up to six months.
The GameChanger
Zilebesiran blocks the final production of angiotensinogen at the hepatic level making it safer from a renal perspective than the ACEis or ARBs. A single subcutaneous injection provides therapy for up to six months.
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
Reference
Desai AS, Webb DJ, Taubel J, et al. Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension. N Engl J Med. 2023 Jul 20;389(3):228-238. doi: 10.1056/NEJMoa2208391. PMID: 37467498.
https://www.nejm.org/doi/full/10.1056/NEJMoa2208391

Pharmacist Members, REDEEM YOUR CPE HERE!

Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)
CPE Information

Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Describe the mechanism of action of Zilebesiran
2. Discuss possible advantages and disadvantages of this drug in the treatment of hypertension
0.05 CEU/0.5 Hr
UAN: 0107-0000-23-323-H01-P
Initial release date: 10/16 /2023
Expiration date: 10/16/2024
Additional CPE details can be found here.

Follow CEimpact on Social Media:
LinkedIn
Instagram

  continue reading

275 episoder

Artwork
iconDel
 
Manage episode 379944714 series 2931422
Indhold leveret af CEimpact. Alt podcastindhold inklusive episoder, grafik og podcastbeskrivelser uploades og leveres direkte af CEimpact eller deres podcastplatformspartner. Hvis du mener, at nogen bruger dit ophavsretligt beskyttede værk uden din tilladelse, kan du følge processen beskrevet her https://da.player.fm/legal.

Injectable, long-acting therapy is a new frontier for hypertension management. Join host, Geoff Wall, as he evaluates zilebesiran, a hepatic angiotensinogen blocker for blood pressure control for up to six months.
The GameChanger
Zilebesiran blocks the final production of angiotensinogen at the hepatic level making it safer from a renal perspective than the ACEis or ARBs. A single subcutaneous injection provides therapy for up to six months.
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
Reference
Desai AS, Webb DJ, Taubel J, et al. Zilebesiran, an RNA Interference Therapeutic Agent for Hypertension. N Engl J Med. 2023 Jul 20;389(3):228-238. doi: 10.1056/NEJMoa2208391. PMID: 37467498.
https://www.nejm.org/doi/full/10.1056/NEJMoa2208391

Pharmacist Members, REDEEM YOUR CPE HERE!

Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)
CPE Information

Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Describe the mechanism of action of Zilebesiran
2. Discuss possible advantages and disadvantages of this drug in the treatment of hypertension
0.05 CEU/0.5 Hr
UAN: 0107-0000-23-323-H01-P
Initial release date: 10/16 /2023
Expiration date: 10/16/2024
Additional CPE details can be found here.

Follow CEimpact on Social Media:
LinkedIn
Instagram

  continue reading

275 episoder

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