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DKBmed Radio provides health care clinicians with expert insight and analysis in a wide variety of disease states and specialty areas. Earn continuing medical education (CME) credit by listening to the episode and visiting our website linked in the episode description. Visit https://dkbmed.com/ for more information and CME opportunities. Hosted on Acast. See acast.com/privacy for more information.
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People living with HIV who’ve had criminal legal involvement face significant challenges that complicate their ability to remain in the HIV care continuum. Many, while incarcerated, have stopped treatment, and once back in the community have been reluctant to resume ART. Why? What are the key drivers behind their disengagement from care? What can c…
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In this issue: Fatigue. It’s one of the most common complaints providers hear from their patients with MS. It interferes with virtually every aspect of a patient’s life. What can clinicians do to better identify MS fatigue? And what do they need to know to better provide management effectively tailored to each patient? Take our post-test to claim C…
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In this issue: POMS. Pediatric Onset Multiple Sclerosis: children and adolescents with symptoms indicating a diagnosis of multiple sclerosis. Are their presentations different from adult-onset MS? POMS is often associated with higher degrees of activity and inflammation early in the disease. How can clinicians most effectively confirm an early MS d…
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Widespread use of highly effective ART has increased the life expectancy of people living with HIV (PLWH) to close to that of the general population. But despite highly effective viral suppression, the risks for cardiovascular diseases continue to increase in these individuals. So too do the risks of neurocognitive impairment. Post-test for CME cre…
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Current ART regimens can successfully manage HIV infection in nearly all PLWH. But what happens when a patient with HIV is coinfected with a dangerous pathogen ART alone cannot handle? Two of the most common are hepatitis B and latent tuberculosis infection. Post-test for CME credits: https://elit.dkbmed.com/issues/203/test Hosted on Acast. See aca…
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Pregnancy and menopause — for many women, these are two of the most significant healthcare events in their lives. For WLWH (women living with HIV) and their healthcare providers, managing these life-changing periods is often complicated by many questions. Post-test for CME credits: https://elit.dkbmed.com/issues/201 Hosted on Acast. See acast.com/p…
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Mild asthma. For patients showing wheezing and shortness of breath on moderate exertion, it’s one of the most common diagnoses, even when breath sounds are clear and pulmonary function testing is normal. What makes mild asthma “mild”? The key guidelines base the stage of a patient’s asthma on how difficult it is to treat. Does that mean the frequen…
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Pulmonary hypertension. The 2022 ESC/ERS revised guidelines have redefined it. New evidence from ongoing and completed clinical trials have led to updates in diagnostic thresholds and treatment algorithms. New agents — some approved, others advancing through the pipeline — promise improved efficacy and safety for a variety of patients. What does it…
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In part 1 of this eHIV Review Special Edition (still available at eHIVreview.org), eHIV Review Program Director Justin Alves, Nurse Educator at Boston Medical Center, reviewed the recent evidence describing some of the barriers to care experienced by marginalized individuals at risk for or living with HIV. In this Part 2 issue, he again calls upon …
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Marginalized individuals at risk for or living with HIV — the formerly incarcerated, immigrants, people with unstable housing, residents of rural communities, the rising number with substance use disorder — have long faced disparities in obtaining adequate health care. What do HCPs need to know to understand the unique needs of these underserved po…
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Marginalized individuals at risk for or living with HIV — the formerly incarcerated, immigrants, people with unstable housing, residents of rural communities, the rising number with substance use disorder — have long faced disparities in obtaining adequate health care. What do HCPs need to know to understand the unique needs of these underserved po…
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A wealth of evidence confirms that adolescents and young adults (AYA) are indeed a priority population whose needs must be addressed for the US Ending the HIV Epidemic program to be successful. What do providers need to know about AYA to bring more of these patients into the HIV care continuum? What should they be doing? And what should they avoid …
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NfL — neurofilament light, from the blood, not the CSF. Is it a reliable indicator of MS activity, a predictor of relapse-related disability, and a monitor of treatment efficacy? OCT — optical coherence tomography. Fast, safe, reliable, and repeatable, it can reveal the cellular layers inside the retina. But how well does what OCT shows correlate w…
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A wealth of evidence confirms that adolescents and young adults (AYA) are indeed a priority population whose needs must be addressed for the US Ending the HIV Epidemic program to be successful. What do providers need to know about AYA to bring more of these patients into the HIV care continuum? What should they be doing? And what should they avoid …
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Has the place for BTK inhibitors in MS been determined? How well do extended interval or alternative B cell depletion dosing regimens work, and for which patients? Do the data support HSCT (hematopoietic stem cell transplant) over high-efficacy DMT — again, for which patients, and with what efficacy and safety? Join us, as guest host Dr. Cole Harri…
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What’s the evidence supporting the existence of an MS prodromal phase — where the biology of the disease has begun but the symptoms typical of MS have not yet appeared? Are there biomarkers to help identify it? Imaging abnormalities? And how can diagnosing a prodrome benefit patients? Join us as we discuss these questions with Dr. Naila Makhani fro…
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Clinicians prescribing the increasingly higher efficacy B-cell depletion or S1P modulators therapies — how aware are they of the newer concerns about safety? Which of their patients may be in greater danger of acquiring PML and/or opportunistic infections? The vaccinations commonly recommended for the general population (eg, COVID-19) — do individu…
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Why do cisgender and transgender women, and particularly women of color, account for such a disproportionate percentage of HIV infections in the US? Why are so many so reluctant to accept PrEP? What can clinicians do to bridge this critical gap in essential HIV services? These are some of the questions Guest Author Dr. Kathleen McManus, from the Di…
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Too many individuals with MS are not receiving access to the most effective care. Why? What’s behind these disparities? And what can individual clinicians do to help remove the barriers that prevent equitable care for all patients?Join us, as Dr. Dorlan Kimbrough, from the division of Neurology, Multiple Sclerosis, and Neuroimmunology at the Duke U…
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Non-nucleoside reverse transcriptase inhibitors (NNRTIs). Rilpivirine, in combination with cabotegravir, provides a long-acting injectable option for both treatment and PrEP. But what risk factors have been associated with virologic failure? Doravirine appears to provide a favorable impact on weight and lipid outcomes, but with a lower genetic barr…
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How burdensome is spasticity for patients with MS? What’s the approach to treatment, and how effective is it? What do patients and clinicians need to know about cannabis-based therapies? These are the key questions Program Director Dr. Michael Kornberg from the Johns Hopkins School of Medicine discusses with guest MS spasticity experts in this seco…
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Hepatitis B. It may not be curable yet, but as our knowledge continues to grow, so does our ability to benefit our patients today as we prepare them for tomorrow. That’s the focus of this Special HBV Edition of eViralHepatitis Review. The first part of this program presented an evidence-based expert commentary by eViralHepatitis Review Program Dire…
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In her Expert Commentary, Dr. Melanie Ward from West Virginia University’s Rockefeller Neuroscience Institute provided analysis of the newer data describing the modifiable and nonmodifiable risk factors for developing MS and/or increasing the rate of disease progression and disability. Join us for this podcast as Dr. Ward explains how these finding…
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Dr. Paul Auwaerter discusses XBB and XBB.1.5 subvariants and the respiratory virus season. Topics: *Why XBB and XBB.1.5 subvariants are more transmissible than other subvariants, but less virulent *Effect of Paxlovid on hospitalization and mortality *Summary of the flu and RSV season *Deciding when to treat a COVID-19 patient Post-test for CME/CE c…
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Stigma. What is it, and where does it come from? How do LGBTQ+ individuals, particularly those with HIV, experience it? How does stigma affect their mental health? What effect does it have on their engagement in HIV care? What do health care providers need to change to minimize stigma in their practices? These are some of the questions advanced pra…
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Individuals with cystic fibrosis — adults as well infants and children — have long struggled to gain and maintain their weight. But how has the current widespread use of highly effective modulator treatments — HEMT — changed that situation? That’s the focus of this eCysticFibrosis Review Special Edition: CF and Nutrition and HEMT.  The first part o…
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Treatment-experienced patients with RAMs — resistance-associated mutations — remain a difficult management challenge. Every case of HIV drug resistance requires a therapeutic regimen individualized for each patient’s ART history. How will new and in-development agents affect the equation? Which drug combinations are right? Where does the balance be…
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How aware are clinicians that MS should no longer be considered a “White people only” disease? What roles have race and ethnicity been shown to play in MS disease severity and disability progression? What do health care professionals need to know to provide the most effective care for all their patients? Join Dr. Yujie Wang from the University of W…
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The advent of triple CFTR modulator therapy – ETI (elexacaftor/tezacaftor/ivacaftor) — poses a number of clinical questions. Are three agents really better than two? For which patients, in what circumstances? What does the CF Team need to understand to ensure their patients get maximum benefit? Join us as we explore these questions with guest autho…
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Most people living with HIV gain weight when initiating ART. For some, the weight gain signifies a “return to health”; for others, the additional weight can be clinically significant and may be strongly associated with an increased risk of metabolic abnormalities. What causes this weight gain? How can patients most at risk for weight-related comorb…
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Where’s the newer MS research leading? How has our understanding of noninflammatory progressive MS changed? How might these findings affect what happens in the clinic? Join us as we discuss these and other questions with Dr. Michael Kornberg from the Johns Hopkins School of Medicine in this eMultipleSclerosis Review podcast. Take our post-test to c…
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Dr. Paul Auwaerter interviews Dr. Michael Mina about COVID-19 testing. Topics: *Why are we seeing prolonged antigen positive test results? *Do we know when someone is infectious? For how long? *Speculating on the cause of Paxlovid rebound Post-test for CME/CE credit: https://covid19.dkbmed.com/multispecialty/7-28-22-episode/eval Access our resource…
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Dr. Paul Auwaerter interviews Dr. Michael Mina about COVID-19 immunity. Topics: *Is COVID-19 here to stay? *Immunity evasiveness of Omicron BA.4 and BA.5 *Expectations for the fall and winter 2022 *Thoughts on upcoming booster reformulation *Should you get a booster now or wait? Post-test for CME/CE credit: https://covid19.dkbmed.com/multispecialty…
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Is it true that a significant number of patients being treated for MS may not actually have the disease? What are the red flags — warnings that something about the patient’s condition does not meet the accepted MS diagnostic criteria — that need to be investigated? Join us in this eMultipleSclerosis Review podcast, as Neuroimmunologist Dr. Gabriell…
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In this Issue: Fatigue. Urinary dysfunction. Constipation. Spasticity and gait problems. Providing relief from these common MS symptoms often requires clinicians to go beyond the prescription pad to recommend nonpharmacologic treatments. What works? What doesn’t? What does the evidence say? Join us as Dr. W. Oliver Tobin from the Mayo Clinic discus…
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Are PLWH at higher risk for increased mortality from COVID-19 infection? How important is it for PWLH to get vaccinated and boosted? Is breakthrough COVID-19 infection more likely to occur among PLWH? What about “long COVID” (PASC)? Join Clinical Research Nurse Diane Kanjilal, manager of the Infectious Disease Clinical Research Unit at Massachusett…
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What was it like for a frontline critical care pulmonologist at the very beginning of the COVID-19 epidemic? On the frontlines as the epidemic became pandemic? What’s it like today, with new variants and new in-patient and out-patient treatments? What are the key differences between then and now, what have we learned, and how can we be better prepa…
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Managing pulmonary exacerbations in people with cystic fibrosis: is there high-grade evidence to support best practices? How helpful is the most current guidance? Does the recent research challenge the current standard of care? Join us for this eCysticFibrosis Review podcast, as Dr. D.B. Sanders from the Indiana University School of Medicine explai…
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Dr. Paul Auwaerter discusses COVID-19 vaccine boosters. Topics: *Should your patients get the booster now or wait? *FDA advisory committee votes to include Omicron component in COVID-19 booster vaccines *COVID-19 case and mortality projections for this winter *Booster timing for children and adults Post-test for CME/CE credit: https://covid19.dkbme…
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Race and ethnicity. How do they affect a patient’s ability to receive a timely and accurate cystic fibrosis diagnosis? How do the social determinants of health limit access to appropriate CF treatment and produce poorer outcomes? That’s what we’re here to talk about today with Dr. Jennifer Taylor-Cousar from National Jewish Health and Children’s Ho…
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Dr. Paul Auwaerter discusses the current state of COVID-19 including treatment updates. Topics: *Information on new Omicron subvariants *CDC advisory about rebound COVID-19 *Latest treatment information *Post-COVID conditions Post-test for CME/CE credit: https://covid19.dkbmed.com/multispecialty/6-1-22-episode/eval Access our resource center, downl…
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Dr. Paul Auwaerter discusses the effect of the Omicron variant, including its subvariants, on COVID-19 vaccines. Topics: *Impact of Omicron on mRNA boosters *Analyzing Omicron and BA.2 subvariants *Interpreting CDC vaccine data *Protection level of one-way masking Post-test for CME/CE credit: https://covid19.dkbmed.com/multispecialty/5-11-22-episod…
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Paul G. Auwaerter, MD, MBA, FIDSA and Michael Angarone, DO, FIDSA discuss the latest guidelines for prevention of COVID-19. Topics: *Updates on the BA.2 subvariant *Who should get a second booster? And when? *What conditions and factors place people at higher risk for severe COVID? *Pre-exposure prophylaxis for COVID-19 prevention *Mitigating risk …
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Paul G. Auwaerter, MD, MBA, FIDSA and David Klimpl, MD discuss current treatments for patients hospitalized with COVID-19. Topics: *New data on efficacy of available therapies *Immunomodulators for critical care patients *Updated NIH recommendations Post-test for CME/CE credit: https://covid19.dkbmed.com/multispecialty/4-6-22-episode/eval Access ou…
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Long-acting injectable antiretroviral therapy is expected to improve adherence, reduce patient burden, and lower community viral load. But for which patients is it suitable? Can it be used as pre-exposure prophylaxis? How does the promise of long-acting ART actually mean in practice?Join us for this eHIV Review podcast, as Dr. Tanya…
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Dr. Paul Auwaerter discusses new vaccine boosters, global impact of the pandemic, and the BA.2 Subvariant. Topics: *New boosters in the future? *Challenges of additional boosters *Cardiac concerns with COVID-19 vaccines? *Collateral effects from the pandemic *Latest news on BA.2 Subvariant Post-test for CME/CE credit: https://covid19.dkbmed.com/mul…
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Dr. Paul Auwaerter discusses the BA.2 Subvariant and the recent authorization from the FDA for second booster dose. Topics: *Virulence of BA.2 vs Omicron and Delta * Therapeutic activity of monoclonal antibodies against BA.2 *Details of approval for booster #2 (4th and 5th dose) *Are there advantages to mixing mRNA vaccines? Post-test for CME/CE cr…
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Dr. Paul Auwaerter discusses what we learned from the COVID-19 pandemic. Topics: *Reviewing the timeline of events and variants *What happens next? *Preparing for the future *The new role of monoclonal antibodies Post-test for CME/CE credit: https://covid19.dkbmed.com/multispecialty/3-24-22-episode/eval Access our resource center, download webinar …
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Twenty percent of new HIV diagnoses occur among adolescents and young adults. They’re a population underserved by HIV prevention resources, with lower retention in HIV care. Their awareness and uptake of PrEP has been and remains low. What can their clinicians do to more effectively help these vulnerable young people? Join Dr. Luis Rubio from Unive…
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