The Memo By Howard Marks podcast

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Medical advancements don’t just spring up—they happen by building on decades of previous discoveries. Today, one of these advancements might be on the verge of another breakthrough. But what had to happen first for it to exist? In this episode, co-hosts Dr. Raven Baxter and Dr. Ronald Gamble explore how a vaccine candidate for a deadly, once-mysterious bacterial disease came to be. The story takes them from one doctor’s groundbreaking connection in the 70s, all the way to a real lab where vaccines are being developed today. Featured Guests : – Carol Baker, Pediatric Infectious Disease Specialist – Isis Kanevsky, Senior Director, Vaccines, Pfizer – Ksenia Krylova, Senior Director, Vaccines, Pfizer Dive into the episode here : 02:54 - Getting into the problem 05:11 - The basics of immunity and vaccine science 09:32 - What is a conjugate vaccine? 14:44 - Group B Strep: A case study 22:23 - Talking to a GBS pioneer 31:40 - A trip to the lab 43:08 - What's next, and closing thoughts Season 5 of Science Will Win is created by Pfizer and hosted by Dr. Raven Baxter and Dr. Ronald Gamble. It’s produced by Acast Creative Studios. Check out our social media platforms to take a deeper look into the labs and stories we discuss during the episodes: Instagram (@pfizerinc), TikTok (@pfizer) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.…

The Memo by Howard Marks

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On October 12, 1990, Oaktree Co-Chairman Howard Marks published his first memo to clients. In the decades since, he has periodically released memos reflecting his viewpoint on the investment landscape, as well as more general business insights. On this podcast we'll hear the latest memos by Howard, released in tandem with or shortly after their publication.

73 episoder

The Memo by Howard Marks

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73 episoder

#MBA #Oaktree Capital Management #Trading #Business

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1
Cockroaches in the Coal Mine 24:29

for 11 hours siden24:29

24:29

In his latest memo, Howard Marks examines the recent string of well-publicized credit problems. He considers how they serve as a reminder that the yield premium offered by sub-investment grade credit isn’t a freebie, but rather compensation for bearing credit risk. While good times lead to complacency and elevated risk tolerance, bad times expose the results of that carelessness. Howard emphasizes that it’s essential to always balance the desire to put money to work with the need for prudence. You can read the memo here ( https://oaktreecapital.com/insights/memo/cockroaches-in-the-coal-mine ).…

1
A Look Under the Hood 28:47

for 9 dage siden28:47

28:47

In his latest memo, Howard Marks offers observations based on his meeting with the board, consultant, and senior staff of a state pension fund. Howard explores the key topics covered during the session, including determining an appropriate risk posture, selecting an investment approach, and assessing performance. While these decisions are challenging, the board and its consultant applied the only reasonable method: asking the right questions and pursuing rational conclusions. You can read the memo here ( https://oaktreecapital.com/insights/memo/a-look-under-the-hood ).…

1
35 Years of Memos 30:47

for 24 dage siden30:47

30:47

To celebrate the 35th anniversary of his memos, Howard Marks recently held a fireside chat for Oaktree employees. Listen to an excerpt from the conversation to hear Howard discuss why he started writing and why he’s kept at it, and learn more about the enduring investment truths encapsulated by his memos.…

1
The Calculus of Value 41:40

for 12 weeks siden41:40

41:40

In his latest memo, Howard Marks sets forth the essence of value and price, as well as the critical relationship between the two. He posits that value exerts a ‘‘magnetic’’ influence on price, meaning the relationship of price to value should be expected to strongly influence investment performance in the long run, with high valuations presaging low subsequent returns, and vice versa. In the context of today’s elevated U.S. equity valuations and widespread investor optimism, he advises us to consider going to an ‘‘Investment Readiness Condition’’ in which investors shift their portfolios somewhat in the direction of increased defense. You can read the memo here (https://www.oaktreecapital.com/insights/memo/the-calculus-of-value).…

1
More on Repealing the Laws of Economics 39:39

for 20 weeks siden39:39

39:39

In his latest memo, Howard Marks discusses the implications of governmental intervention in economies. Considering examples such as rent control, fire insurance, and tariffs, he emphasizes that while free markets don’t produce perfect solutions, efforts to control them often make things much worse. He argues that when allowed to function, the laws of economics create prosperity through incentivizing innovation and productivity. He also touches on the U.S. fiscal deficit, questioning how much longer the government can continue spending more than it takes in. You can read the memo here (https://www.oaktreecapital.com/insights/memo/more-on-repealing-the-laws-of-economics).…

1
30 Years of Oaktree 22:03

for 26 weeks siden22:03

22:03

In celebration of Oaktree’s 30th anniversary on April 10, 2025, cofounders Howard Marks (Co-Chairman), Bruce Karsh (Co-Chairman and Chief Investment Officer), and Sheldon Stone (Principal and Co-Portfolio Manager, High Yield Bonds) held a fireside chat for employees where they shared stories about Oaktree’s origins and the firm’s journey over the last three decades. We’re excited to share an excerpt from their conversation.…

1
Nobody Knows (Yet Again) 35:16

for 30 weeks siden35:16

35:16

In his latest memo, Howard discusses how the recent events surrounding tariffs can have a seismic but unpredictable impact on the global economy. Seismic in that they reflect a fundamental undoing of longstanding norms, and unpredictable in that tariffs would bring untold second- and third-order consequences. He emphasizes that there is no foreknowledge here, with forecasts even less likely to be accurate than usual. Howard considers the response of the financial markets, highlighting the key question regards the appropriateness of the market reaction thus far: has it been just right, excessive, or inadequate? You can read the memo here (https://www.oaktreecapital.com/insights/memo/nobody-knows-yet-again).…

1
Gimme Credit 29:29

for 35 weeks siden29:29

29:29

In his latest memo, Howard addresses a common question he’s been receiving over the last few months: “What about credit spreads?” He explains that the key question should be whether today’s spread is sufficient to offset the credit losses that’ll occur, rather than whether it’s historically narrow or not. Further, he emphasizes that spread widening is a short-term phenomenon and expresses his belief that the elevated yield offered by credit presents a better deal than equities, even at today’s spreads. You can read the memo here (https://www.oaktreecapital.com/insights/memo/gimme-credit).…

1
Behind The Memo: On Bubble Watch 25:26

for 36 weeks siden25:26

25:26

In the latest episode of Behind the Memo , Howard discusses his recent memo, On Bubble Watch, which revisits a subject he first wrote about 25 years ago. He delves into the investor psychology that underpins a market bubble, and assesses the danger of letting excitement and fear of missing out override risk aversion. You can listen to or read the Memo here ( https://www.oaktreecapital.com/insights/memo/on-bubble-watch ).…

1
On Bubble Watch 35:28

for 43 weeks siden35:28

35:28

On January 2, 2000, Howard Marks published his first memo to garner any reader response, bubble.com , calling attention to excesses he detected in the market for tech and internet stocks. His newest memo revisits the subject of bubbles. Howard expresses his view that they’re more a state of mind than a quantitative calculation and describes bubble thinking as irrational, often underlaid by a widespread belief that ‘‘this time is different.’’ Rather than opining on whether we’re in a bubble, Howard lists the signs he sees today and suggests how you might think about them . . . just as he did 25 years ago. You can read the memo here (https://www.oaktreecapital.com/insights/memo/on-bubble-watch).…

1
Ruminating on Asset Allocation 26:33

for 1 year siden26:33

26:33

In his latest memo, Howard Marks outlines the need to base asset allocation decisions around an established risk target. He describes the fundamental differences between ownership and debt, as well as the importance of finding the combination of the two that gets an investor’s portfolio to the desired position on the risk/return continuum. Finally, he expands on the increased utility of debt investments in today’s portfolios. You can read the memo here (https://www.oaktreecapital.com/docs/default-source/default-document-library/ruminating-on-asset-allocation.pdf?sfvrsn=67775566_2).…

1
Shall We Repeal The Laws of Economics? 55:00

for 1 year siden55:00

55:00

In his latest memo, Howard Marks discusses the economic facts of life, as he examines the workings of free markets and what happens when they’re tampered with. He considers what “price-gouging” actually means and how rents should be set. He ultimately argues that the laws of economics shouldn’t be overridden — even when it’s politically advantageous to do so – because of the loss to society. You can read the memo here ( https://www.oaktreecapital.com/docs/default-source/memos/shall-we-repeal-the-laws-of-economics.pdf?sfvrsn=ab205566_1 ).…

1
Behind The Memo: The Impact of Debt with Howard Marks and Morgan Housel 39:14

for 1 year siden39:14

39:14

In this special episode of Behind the Memo, Howard Marks is joined by Morgan Housel, the bestselling author and partner at the Collaborative Fund. They discuss ideas from Howard’s recent memo “The Impact of Debt,” which was inspired by Morgan’s article “How I Think About Debt.” They explore the relationship between leverage and longevity, the nature of risk, and the eternal relevance of Voltaire’s famous saying: “History doesn’t repeat itself. Man always does.” You can listen to or read the Memo here (https://www.oaktreecapital.com/insights/memo-podcast/the-impact-of-debt).…

1
Mr. Market Miscalculates 26:01

for 1 year siden26:01

26:01

In his latest memo, Howard Marks discusses the reasons for the recent market volatility using one of finance’s classic metaphors: Mr. Market, the figure Benjamin Graham created in 1949 to explain the erratic nature of financial markets. Howard pulls together some of his best writing on investor psychology from the past three decades, adds some of his favorite investing cartoons, and offers a few new observations. He suggests that Mr. Market’s lessons about the behavior of markets are as relevant today as they were 75 years ago. You can read the memo here (https://cnt.oaktreecapital.com/docs/default-source/memos/mr-market-miscalculates.pdf?sfvrsn=ddfe5566_1).…

1
Behind the Memo: The Indispensability of Risk with Howard Marks, Bruce Karsh, and Maurice Ashley 32:25

for 1 year siden32:25