Psychedelic Medicine, Value-Based Care & Why Medical School Is Broken with Sebastian Caliri

Joe Lonsdale: American Optimist

Sebastian Caliri is Partner at 8VC with a focus on healthcare investing. Previously, Sebastian spent four years at Palantir where he was responsible for growing its commercial healthcare business. In this episode, Sebastian diagnoses the core problems in U.S. healthcare and explains why traditional fee-for-service care misaligns incentives, resulting in rising costs and inferior health outcomes. He makes the case for new models like value-based care and also highlights the potential of psychedelic medicine and other exciting innovation. Sebastian holds a BS and MS in Molecular Biophysics & Biochemistry from Yale University and spent a year in Stanford's MD program before pursuing a career in tech and investing. He argues that the conventional path in medicine is broken and often produces a risk-averse, complacent culture; he challenges the next generation of doctors and health care professionals to think boldly and take on the status quo.