PT Inquest is an online journal club. Hosted by Jason Tuori, Megan Graham, and Chris Juneau, the show looks at an article every week and discusses how it applies to current physical therapy practice.
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Indhold leveret af The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet. Alt podcastindhold inklusive episoder, grafik og podcastbeskrivelser uploades og leveres direkte af The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet eller deres podcastplatformspartner. Hvis du mener, at nogen bruger dit ophavsretligt beskyttede værk uden din tilladelse, kan du følge processen beskrevet her https://da.player.fm/legal.
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Episode 4: Targeting the Dopamine System to Treat Alcohol Dependence
MP3•Episode hjem
Manage episode 156736432 series 1198471
Indhold leveret af The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet. Alt podcastindhold inklusive episoder, grafik og podcastbeskrivelser uploades og leveres direkte af The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet eller deres podcastplatformspartner. Hvis du mener, at nogen bruger dit ophavsretligt beskyttede værk uden din tilladelse, kan du følge processen beskrevet her https://da.player.fm/legal.
In this episode we meet Pia Steensland and Nitya Jayaram-Lindström from the Centre of Psychiatric Research, Department of Clinical Neuroscience to discuss their research on the evaluation of a dopamine stabiliser OSU6162 for alcohol dependence. Their translational studies show that in alcohol dependent patients OSU6162 reduces craving for alcohol and the animal studies demonstrate that OSU6162 normalises the level of dopamine in the brain reward system, following long- term alcohol consumption which could be the mechanism by which this compound mediates in effects. We discuss the implications of these findings for the indication of alcohol dependence and future directions with regards to OSU6162. To read more about on the studie visit http://ki.se/en/news/one-step-closer-to-a-new-drug-for-alcohol-dependence and to read more about their research in general visit http://ki.se/en/cns/johan-francks-research-group
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4 episoder
MP3•Episode hjem
Manage episode 156736432 series 1198471
Indhold leveret af The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet. Alt podcastindhold inklusive episoder, grafik og podcastbeskrivelser uploades og leveres direkte af The Department of Clinical Neuroscience, Karolinska Institutet, The Department of Clinical Neuroscience, and Karolinska Institutet eller deres podcastplatformspartner. Hvis du mener, at nogen bruger dit ophavsretligt beskyttede værk uden din tilladelse, kan du følge processen beskrevet her https://da.player.fm/legal.
In this episode we meet Pia Steensland and Nitya Jayaram-Lindström from the Centre of Psychiatric Research, Department of Clinical Neuroscience to discuss their research on the evaluation of a dopamine stabiliser OSU6162 for alcohol dependence. Their translational studies show that in alcohol dependent patients OSU6162 reduces craving for alcohol and the animal studies demonstrate that OSU6162 normalises the level of dopamine in the brain reward system, following long- term alcohol consumption which could be the mechanism by which this compound mediates in effects. We discuss the implications of these findings for the indication of alcohol dependence and future directions with regards to OSU6162. To read more about on the studie visit http://ki.se/en/news/one-step-closer-to-a-new-drug-for-alcohol-dependence and to read more about their research in general visit http://ki.se/en/cns/johan-francks-research-group
…
continue reading
4 episoder
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