Bedste JAMAevidence-podcasts (2024)

1
Interim Analyses During Group Sequential Trials With Dr Meurer 16:14

25d ago16:14

16:14

William J. Meurer, MD, MS, University of Michigan Medical School, discusses Interim Analyses During Group Sequential Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Interim Analyses During Group Sequential Clinical Trials

1
Teachers' Guides to the Users' Guides 14:56

2M ago14:56

14:56

Mark C. Wilson MD, MPH, University of Iowa, discusses Teachers’ Guides to the Users’ Guides with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: Evidence vs Consensus in Clinical Practice Guidelines How to Interpret and Use a Clinical Practice Guideline or Recommendation

1
Genome-Wide Association Studies With Dr Rotter 23:26

3M ago23:26

23:26

Jerome I. Rotter, MD, The Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Department of Pediatrics, Harbor-UCLA Medical Center, discusses Genome-Wide Association Studies with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Genome-Wide Association Studies…

1
Conditional Power: How Likely Is Trial Success? 16:28

4M ago16:28

16:28

Benjamin R. Saville, PhD, president and lead statistical scientist of Adaptix Trials, LLC and adjoint associate professor of biostatistics at Vanderbilt University Medical Center, discusses Conditional Power: How Likely Is Trial Success? with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Conditional Power…

1
Bayesian Hierarchical Models With Dr McGlothlin 15:07

5M ago15:07

15:07

Anna E. McGlothlin, PhD, Berry Consultants, LLC, discusses Bayesian Hierarchical Models with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Bayesian Hierarchical Models

1
Sequential, Multiple Assignment, Randomized Trial Designs With Dr Kidwell 13:27

6M ago13:27

13:27

Kelley Kidwell, PhD, professor of biostatistics, University of Michigan, discusses Sequential, Multiple Assignment, Randomized Trial Designs with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Sequential, Multiple Assignment, Randomized Trial Designs

1
Clinical Diagnosis of Dislocated Hips in Newborns 12:18

7M ago12:18

12:18

Dislocated hips in newborns can lead to complex surgery, interruption to family life, and premature osteoarthritis. Daniel Perry, MBChb(Hons), PhD, of Alder Hey Children's Hospital, University of Liverpool, discusses the clinical diagnosis of dislocated hips in newborns with JAMA Associate Editor David Simel, MD, MHS. Related Content: Does This Inf…

1
Target Trial Emulation for Causal Inference From Observational Data With Dr Hernán 27:25

7M ago27:25

27:25

Miguel A. Hernán, MD, DrPH, professor of epidemiology, Harvard T.H. Chan School of Public Health, discusses Target Trial Emulation: A Framework for Causal Inference From Observational Data with JAMA Statistical Editor Roger J. Lewis, MD, PhD. Related Content: Target Trial Emulation

1
On Deep Learning for Medical Image Analysis With Dr Carin 22:54

8M ago22:54

22:54

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses On Deep Learning for Medical Image Analysis with Lawrence Carin, PhD. Related Content: On Deep Learning for Medical Image Analysis

1
Patient-Reported Outcome Measures in Clinical Research With Drs Weinfurt and Reeve 22:10

9M ago22:10

22:10

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Patient-Reported Outcome Measures in Clinical Research with Kevin P. Weinfurt, PhD, and Bryce B. Reeve, PhD. Related Content: Patient-Reported Outcome Measures in Clinical Research

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Does This Child With High Blood Pressure Have Secondary Hypertension? With Dr Nugent 19:33

10M ago19:33

19:33

JAMA Associate Editor David L. Simel, MD, MHS, discusses Does This Child With High Blood Pressure Have Secondary Hypertension? with James T. Nugent, MD, MPH. Related Content: Does This Child With High Blood Pressure Have Secondary Hypertension?

1
Immortal Time Bias in Observational Studies With Dr Kabir Yadav 15:06

11M ago15:06

15:06

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Immortal Time Bias in Observational Studies with Kabir Yadav, MDCM, MS, MSHS. Related Content: Immortal Time Bias in Observational Studies

1
Adjustment for Baseline Characteristics in Randomized Clinical Trials 18:15

12M ago18:15

18:15

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Adjustment for Baseline Characteristics in Randomized Clinical Trial with Lars W. Andersen, MD, MPH, PhD, DMSc. Related Content: Adjustment for Baseline Characteristics in Randomized Clinical Trials

1
Odds Ratios—Current Best Practice and Use With Dr Norton 12:19

1y ago12:19

12:19

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Odds Ratios—Current Best Practice and Use with Edward C. Norton, PhD. Related Content: Odds Ratios—Current Best Practice and Use Types and Distribution of Payments From Industry to Physicians in 2015

1
Assessing the Strength of Recommendations: The GRADE Approach With Dr Vandvik 15:55

1y ago15:55

15:55

Gordon H. Guyatt, MD, MSc, discusses Assessing the Strength of Recommendations: The GRADE Approach with Per Olav Vandvik, MD, PhD. Related Content: How to Interpret and Use a Clinical Practice Guideline or Recommendation

1
Understanding and Applying the Results of a Systematic Review With Dr Murad 16:27

1y ago16:27

16:27

Host Gordon Guyatt, MD, MSc, discusses Understanding and Applying the Results of a Systematic Review with M. Hassan Murad, MD, MPH. Related Content: How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care Acute Treatments for Episodic Migraine in Adults

1
Estimands, Estimators, and Estimates With Dr Little 22:06

1+ y ago22:06

22:06

Roger J. Lewis, MD, PhD, discusses Estimands, Estimators, and Estimates with Roderick J. Little, PhD, in the JAMA Guide to Statistics and Methods series. Related Content: Estimands, Estimators, and Estimates

1
Fixed-Effects and Random-Effects Models With Dr Murad 20:30

1+ y ago20:30

20:30

Gordon H. Guyatt, MD, MSc, discusses Fixed-Effects and Random-Effects Models with M. Hassan Murad, MD. Related Content: Random-Effects Meta-analysis

1
Does This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection? With Dr Johnson 19:43

1+ y ago19:43

19:43

David L. Simel, MD, discusses Does This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection? with Davin Johnson, MD. Related Content: Does This Patient With Acute Infectious Conjunctivitis Have a Bacterial Infection?

1
Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses With Dr Smith 18:25

1+ y ago18:25

18:25

Roger J. Lewis, MD, PhD, discusses Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses with Valerie A. Smith, DrPH. Related Content: Interpreting the Results of Intention-to-Treat, Per-Protocol, and As-Treated Analyses of Clinical Trials

1
Time-to-Event Analysis With Dr Tolles 11:19

1+ y ago11:19

11:19

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Time-to-Event Analysis with Juliana Tolles, MD, MHS. Related Content: Time-to-Event Analysis

1
Adjusted Analyses in Studies Addressing Therapy and Harm With Dr Agoritsas 17:22

2y ago17:22

17:22

Gordon H. Guyatt, MD, MSc, discusses Adjusted Analyses in Studies Addressing Therapy and Harm with Thomas Agoritsas, MD, PhD. Related Content: Adjusted Analyses in Studies Addressing Therapy and Harm

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Adjusting for Nonadherence or Stopping Treatments With Drs Adler and Latimer 17:58

2y ago17:58

17:58

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Adjusting for Nonadherence or Stopping Treatments with Amanda I. Adler, MD, PhD, and Nicholas Latimer, PhD. Related Content: Adjusting for Nonadherence or Stopping Treatments in Randomized Clinical Trials

1
Spectrum Bias With Dr Reem A. Mustafa 14:07

2y ago14:07

14:07

Gordon Guyatt, MD, MSc, discusses Spectrum Bias with Reem A. Mustafa. MD, MPH, PhD.

1
Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data With Dr Lachin 17:06

2y ago17:06

17:06

JAMA Statistical Editor Roger J. Lewis, MD, PhD, discusses Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data with John M. Lachin, ScD. Related Content: Worst-Rank Score Methods—A Nonparametric Approach to Informatively Missing Data

1
Discrimination and Calibration of Clinical Prediction Models With Dr Alba 16:46

2y ago16:46

16:46

Gordon Guyatt, MD, MSc, discusses Discrimination and Calibration of Clinical Prediction Models with Ana Carolina Alba, MD, PhD. Related Content: Discrimination and Calibration of Clinical Prediction Models With Dr Alba Read Transcript

1
Using Latent Class Analysis to Identify Hidden Clinical Phenotypes With Dr Heather G. Allore 17:34

2+ y ago17:34

17:34

JAMA Statistical Editor Roger Lewis, MD, PhD, discusses Using Latent Class Analysis to Identify Hidden Clinical Phenotypes with Heather G. Allore, PhD. Related Content:

1
How to Interpret and Use a Clinical Practice Guideline or Recommendation With Dr Gordon Guyatt and Dr Brignardello-Petersen 32:26

2+ y ago32:26

32:26

Host Robert M. Golub, MD, discusses How to Interpret and Use a Clinical Practice Guideline or Recommendation with Gordon H. Guyatt, MD, MSc, and Romina Brignardello-Petersen, DDS, MSc, PhD.

1
Measuring Agreement Beyond Chance With Dr Thomas McGinn 15:00

2+ y ago15:00

15:00

Gordon Guyatt, MD, discusses Measuring Agreement Beyond Chance with Thomas McGinn, MD, MPH. Related Content: Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review

1
Use of Run-in Periods in Randomized Trials With Dr Armitage 19:29

2+ y ago19:29

19:29

JAMA Statistical Editor Roger Lewis, MD, PhD, discusses Use of Run-in Periods in Randomized Trials with Jane M. Armitage, MBBS. Related Content: Use of Run-in Periods in Randomized Trials With Dr Armitage Short- and Long-term Effects of a Mobile Phone App in Conjunction With Brief In-Person Counseling on Physical Activity Among Physically Inactive …

1
Regression Discontinuity Study Design to Estimate Observational Differences With Dr Maciejewski 17:54

2+ y ago17:54

17:54

JAMA Statistical Editor Roger Lewis, MD, discusses Regression Discontinuity Design with Matthew L. Maciejewski, PhD. Related Content: Regression Discontinuity Design Using Instrumental Variables to Address Bias From Unobserved Confounders

1
Correlation and Regression With Dr Jaeschke 15:48

3y ago15:48

15:48

Gordon H. Guyatt, MD, MSc, discusses

1
Does This Adult Patient Have Hypertension? Interview With Dr Anthony Joseph Viera 12:38

3y ago12:38

12:38

David Simel, MD, discusses Does This Patient Have Hypertension? with Anthony J. Viera, MD, MPH. Related Content: Does This Adult Patient Have Hypertension? Interview With Dr Anthony Joseph Viera USPSTF Recommendation: Screening for Hypertension in Adults USPSTF Review: Screening for Hypertension in Adults…

1
Case-Control Studies: Using “Real-world” Evidence to Assess Association, With Dr Irony 23:07

3y ago23:07

23:07

JAMA Statistical Editor Roger Lewis, MD, discusses Case-Control Studies: Using “Real-world” Evidence to Assess Association, With Dr Irony.

1
Economic Analysis With Dr Paul Moayyedi 25:45

3y ago25:45

25:45

Gordon Guyatt, MD, discusses economic analysis with Paul Moayyedi, PhD

1
Equipoise in Research—Integrating Ethics and Science in Human Research 21:48

3y ago21:48

21:48

Roger J. Lewis, MD, PhD, discusses Equipoise in Research—Integrating Ethics and Science in Human Research with Alex John London, PhD Related Content: Equipoise in Research—Integrating Ethics and Science in Human Research

1
Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials 27:31

3y ago27:31

27:31

Roger J. Lewis, MD, PhD, discusses Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials with Melanie Quintana, PhD Related Content: Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among New…

1
Cost-effectiveness Analysis for Clinicians 18:21

3+ y ago18:21

18:21

Cost-effectiveness analysis defines trade-offs between costs, harms, and benefits of alternative treatments and combines them into a single metric, the incremental cost-effectiveness ratio (ICER), that can inform decisions about which interventions to recommend when limited resources are available. Gillian Sanders-Schmidler, PhD, professor of popul…

1
Misleading Presentations of Clinical Trial Results with Dr Victor Montori 31:25

3+ y ago31:25

31:25

Gordon Guyatt, MD, discusses Misleading Presentations of Clinical Trial Results with Victor Montori, MD Related Content: Misleading Presentations of Clinical Trial Results with Dr Victor Montori When Can Intermediate Outcomes Be Used in Clinical Trials? When Guidelines Recommend Shared Decision-making…

1
Does This Patient Have Hip Osteoarthritis? Interview with Dr David Metcalfe 11:54

3+ y ago11:54

11:54

David Simel, MD, discusses Does This Patient Have Hip Osteoarthritis? with David Metcalfe, PhD, MRCP, MRCS, MRCEM

1
Surrogate Outcomes from the Users’ Guides to the Medical Literature 17:25

3+ y ago17:25

17:25

Anne M. Holbrook, MD and Gordon Guyatt, MD, discuss Surrogate Outcomes from the JAMA Users’ Guides to the Medical Literature Related Content: When Can Intermediate Outcomes Be Used as Surrogate Outcomes? FDA Acceptance of Surrogate End Points for Cancer Drug Approval: 1992-2019 What Constitutes a Valid Surrogate End Point in Cancer Clinical Trials?…

1
Multiple Comparison Procedures from the JAMA Guide to Statistics and Methods 22:47

3+ y ago22:47

22:47

JAMA Deputy Editor Edward Livingston, MD, discusses "Multiple Comparison Procedures" with Dr. Jing Cao, PhD

1
Did This Patient Have Cardiac Syncope? Interview with Edward Etchells, MD, MSc 16:34

4y ago16:34

16:34

David Simel, MD, discusses Did This Patient Have Cardiac Syncope? with Edward Etchells, MD, MSc

1
Logistic Regression—What It Is and How to Use It in Clinical Research 32:47

4y ago32:47

32:47

Logistic regression is one of the most commonly used statistical analytic tools in the medical literature. William Meurer, MD, from the University of Michigan, and Juliana Tolles, MD, from UCLA, discuss a JAMA Guide to Statistics and Methods article they wrote entitled “Logistic Regression Diagnostics: Understanding How Well a Model Predicts Outcom…

1
Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods 23:14

4y ago23:14

23:14

Roger J. Lewis, MD, PhD, discusses Randomization in Clinical Trials from the JAMA Guide to Statistics and Methods Related Article(s): Randomization in Clinical Trials

1
How to Read Articles That Use Machine Learning With Yun Liu, PhD 25:29

4y ago25:29

25:29

Interview with Yun Liu, author of How to Read Articles That Use Machine Learning: Users’ Guides to the Medical Literature

1
Will This Patient Be Difficult to Intubate? Interview with Dr Michael Detsky 15:43

4y ago15:43

15:43

Dr David Simel discusses Will This Patient Be Difficult to Intubate? with Dr Michael Detsky

1
The Stepped-Wedge Clinical Trial: Evaluation by Rolling Deployment 18:07

4y ago18:07

18:07

Cluster randomized trials are performed when an intervention must be delivered to a group of patients like when testing new nursing protocols on award or different means for cleaning beds on a ward. One type of cluster trials is called a stepped-wedge where every cluster in the study ultimately undergoes the intervention. How this works it is expla…

1
Minimal Clinically Important Difference: Defining What Really Matters to Patients 11:43

4+ y ago11:43

11:43

JAMA Deputy Editor Edward Livingston, MD, discusses Minimal Clinically Important Difference: Defining What Really Matters to Patients with Anna E. McGlothlin, PhD

1
Sample Size Calculation for a Hypothesis Test With Dr Lynne Stokes 12:14

4+ y ago12:14

12:14

One of the most common causes for problems we see in manuscripts at JAMA is an inappropriately calculated study sample size. This seemingly mysterious process is explained by Lynne Stokes, PhD, professor of Statistical Science at Southern Methodist University in Dallas, Texas.

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