A weekly podcast where Helen, Edison and Ms. Sinclair discuss a movie they’ve all seen, their week in entertainment and an artist whose career they would like to put in focus.
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Welcome to CHAOS- a podcast created by sisters, Harper and Raena. Through this platform, we will explore various topics and through which, hopefully empower our listeners. With a lot of nonsense and a little bit of wisdom, we hope that by listening you will take something away, whether that's food for thought or just a little laugh. Check out our Instagrams: Harper- @sinclair.harper Raena- @raenasinclair
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Longevity by Design is a podcast for individuals looking to experience a longer, healthier life. In each episode, Dr. Gil Blander joins a co-host and an industry expert to explore a personalized health journey. The show helps you access science-backed information, unpack complicated concepts, learn what’s on the cutting edge of longevity research and the scientists behind them. Tune into Longevity by Design and see how to add years onto your life...and life onto your years.
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Unlocking the Secrets of Longevity with Dr. David Sinclair
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In this episode of Longevity by Design, our host Dr. Gil Blander speaks with Dr. David Sinclair, a professor of genetics at Harvard Medical School, about the science behind aging and how we can extend both lifespan and healthspan. Dr. Sinclair shares his groundbreaking research on the role of epigenetic changes in aging and the potential to reverse…
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This week we’re discussing Francis Ford Coppola’s self-financed,giant swing of a film, Megalopolis. Did this Wow (Platinum) us? Or was it a MegaFLOPolis?Af Talk Movie To Me
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It’s the Season 8 premiere! And also a pretty epic mmilestone, as this is the 200th episode of Talk Movie To Me *applause* Speaking of epic, we are launching this season with director Coralie Fargeat’s audacious new film “The Substance”, featuring an absolutely unforgettable performance by Demi Moore. What would you do for a more beautiful, more yo…
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The Impact of Artificial Intelligence, Machine Learning, and Large Language Models on Your Health and Wellness With Dr. Renee Deehan
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In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its applications in health and wellness. Renee explains the differences between AI, machine learning, and large language models (LLMs). She discusses how…
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Start your engines and cover your foreheads in tar because we’re discussing the latest in the Mad Max Saga - Furiosa! In this prequel, George Miller shows us how our titular character, played by Anya Taylor-Joy, came to be. So buckle up and let Hellcat Helen, Sparkplug Edison and Scrapheap Sinclair lead the way.…
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The Surprising Link Between Space Travel and Aging with Dr. David Furman
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On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate Professor at the Buck Institute for Research on Aging. David discusses his groundbreaking research on inflammaging— uncovering how chronic, low-grade i…
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Improvements in Blood and Fitness Tracker Biomarkers in a Digital Health Platform
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In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made through data science and artificial intelligence. Dr. Deehan elaborates on her background in molecular biology and how she transitioned to computatio…
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Parkinson's and Alzheimer's: The Gut-Brain Connection Explored with Dr. Julie Andersen
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In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transformin…
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The impact of ketones on performance and aging with Dr. Brianna Stubbs
1:15:29
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In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competitive rower to becoming a scientist. She dives into her research on ketone biology and its implications for health and aging. Dr. Stubbs discusses the …
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The impact of ultra-processed foods and fructose on metabolic health with Dr. Robert Lustig
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In this episode of Longevity by Design, host Dr. Gil Blander talks with Dr. Robert Lustig, an emeritus professor of pediatrics at UCSF and a renowned neuroendocrinologist. Dr. Lustig dives into the impact of ultra-processed foods and fructose on metabolism, emphasizing how these contribute to obesity and metabolic diseases. He also discusses his jo…
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Ask Me Anything (AMA): Optimizing Health & Longevity with Dr. Gil Blander & Ashley Reaver, MS, RD, CSSD
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In this Longevity by Design Ask Me Anything (AMA) episode with Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, the focus is on user questions about optimizing health and longevity. Dr. Blander discusses the rationale behind InsideTracker's shift to a subscription model, emphasizing the importance of continuous engagement for long-term health impr…
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Understanding Aging to Extend Healthspan and Longevity with Dr. Gordon Lithgow
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In this episode of Longevity by Design, hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander sit down with Dr. Gordon Lithgow, a Professor and Vice President for Academic Affairs at the Buck Institute for Research on Aging. Dr. Lithgow's research focuses on understanding the mechanisms of aging and identifying genes and small molecules that can p…
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On this week’s episode, we're singing songs of love with The Idea of You a film that tries to prove me wrong when I tell all the 20-somethings who message me on dating apps that they’re sweet and naive, but fully wrong when they say age is just a number. Directed by Michael Showalter and starring Annie Hathaway, this film will make you want to dig …
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The Impact of Exercise & Nutrition on Muscle, Tendons, Ligaments, & Aging with Dr. Keith Baar
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In this episode of Longevity By Design, co-hosts Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander welcome renowned professor Dr. Keith Baar. As the head of the Functional Molecular Biology Lab at UC Davis, Dr. Baar has made groundbreaking discoveries about how exercise and nutrition influence the adaptation of muscles, tendons, and ligaments. Durin…
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It’s about to get sweaty in here because this week we’re discussing Challengers, the new film directed by the maestro of desire, Luca Guadagnino. So join us while we chat tennis, thouples, and churros. It’s game on!Af Talk Movie To Me
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The Impact of DNA Damage & Lifestyle on Aging & Longevity Medicine with Dr. Morten Scheibye-Knudsen
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In this episode of Longevity by Design, host Dr. Gil Blander is joined by Dr. Morten Scheibye-Knudsen, a leading figure in aging research. Dr. Scheibye-Knudsen discusses his groundbreaking research on the role of DNA damage in the aging process and its implications for chronic diseases, aging research, and longevity medicine. The goal of his work i…
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This week we observe a world not too dissimilar from the one we know now and through the lens of a war photo journalist; a job that we all agree looks utterly harrowing. We’re talking Alex Garland’s Civil War starring Kirsten Dunst, Wagner Moura and Cailee Spaeny, with a welcomed yet terrifying cameo from Jesse Plemons. Tune in to hear our thoughts…
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It’s got gore, it’s got lore, it’s the directorial debut of Dev Patel! This week we’re discussing Monkey Man! Dev takes some big swings with this one! Join us for a wild ride because this one truly goes apeshit.Af Talk Movie To Me
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The Effects of Cellular Senescence and Senolytics on Healthspan with Dr. James Kirkland
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Do you know what senescent (zombie) cells are and how cellular senescence and senolytics impact health? In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander are joined by Dr. James Kirkland from the Mayo Clinic, one of the world's leading figures in aging research. This episode is a deep dive into aging research, cellular…
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LIGHTS, CAMERA, POSSESSION! This week we’re discussing Late Night with the Devil! It’s time to separate the believers from the skeptics as we conjure up a great conversation about this newly released horror film. Oh and Edison tries to convince us that he has been hypnotized four times.Af Talk Movie To Me
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This week we are throwing on some workout gear and taking you for a wild ride through the neon-lit streets of 1989 for writer-director Rose Glass’s latest film Love Lies Bleeding, starring Kirsten Stewart. With enough twists and turns to make your head spin faster than a protein shake blender, Love Lies Bleeding is the kind of film that leaves you …
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Aging, Mental Health, Suicide Risk & Prevention with Dr. Peter Franz
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This episode of Longevity by Design discusses mental health and suicide risk and prevention. The following topics are discussed: depression, suicide, substance abuse, social isolation, among others also. This episode is intended to raise awareness of mental health issues and suicide risk and prevention. The topics discussed may be distressing or tr…
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Double Feature: Road House & Immaculate
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Award’s season is over so we’re putting prestige films aside to make room for Jake Gyllenhaal’s rockin’ bod Sydney Sweeney’s scream queen debut. That’s right, this week we’re talking the Road House remake streaming on Prime and Immaculate being screened in desperately dark theatres.Af Talk Movie To Me
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This week we dive into the magical world of Hayao Miyazaki! Helen is away, so Edison and Ms. Sinclair are teaming up to discuss Oscar winning film The Boy and the Heron. Come join us for this cosmic adventure!Af Talk Movie To Me
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XPRIZE Healthspan: Revolutionizing Human Aging & Healthspan with Dr. Jamie Justice
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Can we find ways to target human aging and extend healthspan? This ambitious premise is at the heart of XPRIZE Healthspan, a 7-year, $101 million global competition with an audacious challenge: to successfully develop a proactive, accessible therapeutic that restores muscle, cognitive, and immune function by a minimum of 10 years, with a goal of 20…
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Are you ready for some desert drama? Cause we’re gonna dive into the swirling sands of Dune: Part Two. This movie has it all. Intrigue, battles, prophecies, witches, love, lust, laughter. It even has Christopher Walken! So grab your stillsuit and spice melange, people, because we're about to hitch a ride on a giant sand worm and embark on a journey…
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Longevity Genes, Blood Biomarkers of Aging, & Targeting Aging with Metformin with Dr. Nir Barzilai
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Aging is inevitable, but can we influence how we age? In this episode of Longevity by Design, hosts Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, interview Dr. Nir Barzilai—the Director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Resear…
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Slumpuary: This is Me...Now & The Beekeeper
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It's the February Movie Slump! Right on time! And we're diverting from our usual content (discussing movies with a modicum of substance) and bringing you this; Slumpuary: This is Me...Now & The Beekeeper. Have a laugh and judge Edison freely!Af Talk Movie To Me
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The Impact of Exercise on Blood Biomarkers and InsideTracker’s New DNA Healthspan Report with Dr. Bartek Nogal
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In this episode of Longevity by Design, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, sit down with Dr. Bartek Nogal from InsideTracker to explore the cutting-edge intersections of exercise, genetics, blood biomarkers, health optimization, and longevity. Dr. Bartek Nogal, with a strong background in biological engineering and genomics, dives int…
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This week we all have a good cry and discuss Past Lives, the directorial debut from Celine Song. We’re on the road to the Oscars and couldn’t be more excited to chat about this impressive and poignant film!Af Talk Movie To Me
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On this episode, we discuss Jonathan Glazer’s new film, “The Zone of Interest”, which tells the story of Rudolf and his wife, Hedwig, as they go about their very normal, ordinary, hum drum lives just on the other side of the wall from Auschwitz, where Rudolf is a commandant. This film asks the question: Whatever happened to loving thy neighbour?…
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Ask Me Anything (AMA): Oral Health, Healthspan, and Longevity with Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD
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Did you know that your oral health has a profound impact on healthspan and longevity? Do you want to learn about the connections between oral health, healthspan, and longevity and what you can do to improve your oral health to help you live longer and add more healthy years to your life? This episode of Longevity by Design is an Ask Me Anything (AM…
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This week, hold on to your inner child because we're discussing All of Us Strangers from director Andrew Haigh. This film has a truly stacked cast with moving performances from Andrew Scott, Paul Mescal, Claire Foy and Jamie Bell. Tune in to hear our many thoughts!Af Talk Movie To Me
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This week we’re chatting American Fiction! Did this TIFF People’s Choice winner live up to the hype? Did the story leap off the pages into our hearts? Did Jeffrey Wright earn that Oscar nomination? Which Johnny Walker Label would each of us choose? Tune in to find out!Af Talk Movie To Me
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How Our Blood Impacts Brain Aging and Alzheimer’s Disease with Dr. Tony Wyss-Coray
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In this insightful episode of Longevity by Design, hosts Dr. Gil Blander and Ashley Reaver welcome Dr. Tony Wyss-Coray, a distinguished expert in neurology and brain aging. Dr. Wyss-Coray shares his journey from a childhood fascination with nature to becoming a leading figure in neuroscience and immunology. His initial interest in farming evolved i…
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On this week’s episode we get thrown into the ring with sweaty muscle god Zac Efron and his brothers Harris Dickinson, Jeremy Allen White and Stanley Simons, as we wrestle with our emotions in the film “The Iron Claw”. Does this movie have us down for the count, or are we calling it an empty victory? Only one way to find out, ooooohhh yeeeaaahhh!…
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Double Feature: Wonka & Poor Things
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Grab your extra large popcorn, some chocolate and a couple Portuguese custard tarts because we've got a double feature for you! First up is Wonka, starring Timothée Jenner - sorry - Chalamet, in the origin story of the infamous chocolatier. Second is Poor Things, directed by Greek visionary Yorgos Lanthimos, and starring Emma Stone, who delivers th…
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Do NAD Analogs and Resveratrol Boost Cellular Health and Longevity With Dr. Joe Baur
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How can you increase NAD+ levels? And do higher NAD+ levels really lead to better metabolic health? What does the research say on their benefits for longevity? These topics and more are discussed in the latest episode of Longevity by Design with Dr. Joe Baur. Dr. Baur, Professor at the Perelman School of Medicine of the University of Pennsylvania, …
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It’s time to leave 2023 behind film lovers! We’re moving on to 2024 with one of our favourite yearly episodes! It’s Talk Movie To Me’s 7th annual Most Anticipated Episode! Will our picks be hits or major flops? Only time will tell! This year we had a few surprising picks so tune in to hear what we can’t wait to see!…
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Ho! Ho! Hope you’re having a happy holiday season! We are so excited to bring you our 7th Annual Talk Movie To Me Christmas Special, where Helen, Ms Sinclair and Edison have several many cups of cheer and watch three Christmas movies. This year, we’re watching White Christmas, Jingle All the Way, and Elf. You can expect singing, swooning, drunken c…
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Hey listeners, did you also have a dream about Paul Giamatti mushrooms and a late-in-career Nic Cage with horseshoe hair? We knew it! This week we delve in on Dream Scenario from Norwegian director Kristoffer Borgli and we learn that Ms. Sinclair only has nightmares when she dreams.Af Talk Movie To Me
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The Latest Updates in Longevity Research with Dr. Eric Verdin
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This episode of Longevity by Design features an interview with Dr. Eric Verdin—the CEO of The Buck Institute. The Buck Institute was the first center dedicated to aging research, and many discoveries within the aging field have come out of this research center. For this episode, Dr. Verdin, Dr. Blander, and Ashely Reaver sat down in person to discu…
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I hope everyone has enough hot dogs because we’re serving up some melodrama with May December, the new film by Todd Haynes. It’s classy, it’s camp, it has heart, it has teeth, it’s drama, it’s comedy and there is a whole lot to discuss!!Af Talk Movie To Me
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This week we eat the rich! But is Emerald Fennell's new film "Saltburn" a meal where we'd go back for seconds or did we have to choke it down? Join Helen, Ms Sinclair and Edison as they discuss "Saltburn", starring Barry Keoghan and Jacob Elordi.Af Talk Movie To Me
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How To Be Smarter About Protein Intake With Dr. Nick Burd
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Dr. Nick Burd, PhD, is a skeletal muscle physiologist with an expertise in protein metabolism and exercise. In this episode, Dr. Burd discusses the importance of maintaining muscle mass as we age, expressing that “strong is the new healthy.” While adequate protein intake is an important aspect of gaining muscle and maintaining healthspan, many peop…
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Edison is away this week and we have a lovely guest host in his place! Felicia Maroni, friend of the show and fellow movie buff, is here to discuss Justine Triet’s Anatomy of a Fall. There will be spoilers in this episode, you’ve been warned! Felicia hosts her own movie podcast - Seeing Faces in Movies - you can find that wherever you get your podc…
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Hey listener, are you doing absolutely nothing and feeling EXHAUSTED? Well, give your brain something to chew on and listen to our latest episode! This week we’re discussing The Killer directed by David Fincher and starring Michael Fassbender. Is it a bullseye or does this assassin film miss the mark? Tune in to hear our thoughts!…
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Tracking Your Body’s Data to Improve Health Outcomes with Dr. Sara Gottfried
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In this episode of Longevity By Design, Dr. Gil Blander and Ashley Reaver interview Dr. Sara Gottfried. Dr. Gottfried received her MD from Harvard Medical School and completed residency at UCSF, however she is more likely to prescribe a continuous glucose monitor and personalized nutrition plan to her patients than the latest pharmaceutical. This e…
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We’re back with Season 7 of Talk Movie To Me! This week we tease our beehive and rock a perfect cat eye because we’re chatting about Sofia Coppola’s new film Priscilla!Af Talk Movie To Me
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Ask Me Anything: Lowering Cholesterol and Optimizing VO2max
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Did you know that blood cholesterol levels are influenced by far more than just the foods we eat? Are you eager to know how to assess healthspan using your own body's data? This episode of Longevity by Design is an Ask Me Anything between Dr. Gil Blander and Ashley Reaver. We gathered frequently asked questions from the Longevity by Design audience…
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