Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations w ...
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Insightful conversations with leading experts in the field of health care, medical research, policy, and more from the New England Journal of Medicine (NEJM). Each episode examines the many complexities found at the junction of medicine and society.
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Audio podcasts featuring the week’s top medical news plus pertinent interviews
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The House reflects medicine’s most pressing issues through the eyes of residents, providing a forum to share their stories from the bedside, where they are learning far more than the lessons of clinical medicine.
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A Day in the Life is a podcast for medical students, by medical students. Interviews with attendings about daily life and training may help you explore a range of specialties.
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NEJM Interview: Benjamin Rome on the results of the initial round of drug-price negotiation under the Inflation Reduction Act.
9:44
9:44
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Benjamin Rome is a physician and health policy researcher at Brigham and Women’s Hospital and an assistant professor of medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. B.N. Rome, A.S. Kesselheim, and W.B. Feldman. Medicare’s First Round of Drug-Price Negotiation — Measuring Su…
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NEJM This Week — November 21, 2024
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29:57
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Featuring articles on a nationwide couple-based genetic screening; adjunctive embolization for subdural hematoma; a late-liver-stage attenuated malaria vaccine; and climate change, floods, and human health; a review article on Candida auris infections; a case report of a girl with abdominal pain; and Perspectives on Medicare’s first round of drug-p…
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Partners in Diagnosis: ChatGPT, a Mother’s Intuition, and a Doctor’s Expertise with Courtney Hofmann and Dr. Holly Gilmer
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40:06
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In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Courtney Hofmann, a mother whose use of ChatGPT led to her son’s diagnosis of tethered cord syndrome after seeing 17 doctors over three years, and Dr. Holly Gilmer, the pediatric neurosurgeon who confirmed and treated the condition. The conversation explores how AI he…
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NEJM at AHA — Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease
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4:56
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Did you miss AHA 2024? Listen here to brief discussions of the latest research. Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Phase 1 Study of AAV9.LAMP2B Ge…
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NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction
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3:59
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Did you miss AHA 2024? Listen here to brief discussions of the latest research. Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Routine Spironolactone in Acute…
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NEJM at AHA — Intensive Blood-Pressure Control in Patients with Type 2 Diabetes
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Did you miss AHA 2024? Listen here to brief discussions of the latest research. Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Intensive Blood-Pressure Contro…
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NEJM at AHA — Left Atrial Appendage Closure after Ablation for Atrial Fibrillation
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4:29
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Did you miss AHA 2024? Listen here to brief discussions of the latest research. Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Left Atrial Appendage Closure a…
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NEJM at AHA — CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy
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3:55
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Did you miss AHA 2024? Listen here to brief discussions of the latest research. Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — CRISPR-Cas9 Gene Editing with N…
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NEJM at AHA — Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity
4:15
4:15
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4:15
Did you miss AHA 2024? Listen here to brief discussions of the latest research. Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Tirzepatide for Heart Failure w…
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NEJM at AHA — Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia
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2:49
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2:49
Did you miss AHA 2024? Listen here to brief discussions of the latest research. Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Catheter Ablation or Antiarrhyt…
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NEJM Interview: Heather Hsu on an institutional conference series that provides opportunities for addressing the adverse effects of bias and medical racism.
8:27
8:27
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Heather Hsu is a pediatric hospitalist at Boston Medical Center and an assistant professor of pediatrics at the Boston University Chobanian and Avedisian School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. K.A. Nash, J. Perdomo, and H.E. Hsu. Health Equity Rounds — Root-Cause and Solutions-Orient…
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NEJM This Week — November 14, 2024
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25:25
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Featuring articles on perioperative durvalumab in bladder cancer, transcatheter valve repair for mitral regurgitation, chemoradiotherapy in gastric cancer, and lessons from England’s National Health Service; a review article on lung transplantation; a case report of a newborn with hypoxemia and a lung opacity; and Perspectives on our latest brief c…
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The Marburg Virus Outbreak in Rwanda
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33:27
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Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Sabin Nsanzimana, M.D., Ph.D., is the Minister of Health of Rwanda. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. Audio Interview: The Marburg Virus Outbreak in Rwanda. N Engl J Med 2024;39…
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NEJM Interview: Vincent Guilamo-Ramos on the need to rethink the response to HIV in Latino communities.
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7:13
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Vincent Guilamo-Ramos is the executive director of the Institute for Policy Solutions at the Johns Hopkins School of Nursing. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. V. Guilamo-Ramos, M. Thimm-Kaiser, and A. Benzekri. The U.S. Latino HIV Crisis — Ending an Era of Invisibility. N Engl J Med 2024;391:1665-…
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Featuring articles on an invasive treatment strategy in older patients with myocardial infarction, a randomized trial of very early medication abortion, therapies in stage III melanoma, and on long Covid defined; a review article on uterine fibroids; a Clinical Problem-Solving on two sides to the story; and Perspectives on the U.S. Latino HIV crisi…
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NEJM Interview: Liam McCoy on concerns about the implementation of large language models in note writing and related clinical tasks.
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13:41
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Liam McCoy is a resident physician in neurology at the University of Alberta. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L.G. McCoy, A.K. Manrai, and A. Rodman. Large Language Models and the Degradation of the Medical Record. N Engl J Med 2024;391:1561-1564.
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Featuring articles on semaglutide in persons with obesity and knee osteoarthritis, the addition of PI3K inhibition in breast cancer, treatments in older patients with myeloma, and total hip replacement for hip osteoarthritis; a review article on lead poisoning; a case report of a man with dyspnea after old myocardial infarction; and Perspectives on…
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NEJM Interview: Mark Wicclair on approaches to protecting both physicians’ conscience and patients’ health.
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8:02
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Mark Wicclair is an adjunct professor of medicine at the University of Pittsburgh Center for Bioethics and Health Law and a professor of philosophy emeritus at West Virginia University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.B. White and M. Wicclair. Navigating Clinicians’ Conscience-Based Refusals to…
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Featuring articles on treatments in heart failure, advanced non–small-cell lung cancer, and Dupuytren’s contracture; a neurodevelopmental disorder caused by deletion in a long noncoding RNA; a review article on burnout and depression among physicians; a case report of a woman with confusion, aphasia, and a brain mass; a Medicine and Society article…
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NEJM Interview: Jose Figueroa on the potential effects of the results of the 2024 elections on health care access, affordability, and equity.
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21:26
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Jose Figueroa is an associate professor of health policy and management at the Harvard T.H. Chan School of Public Health and an assistant professor of medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.M. McWilliams and S.B. Dusetzina. Affordability of Health Care in the United…
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Featuring articles on nivolumab in advanced Hodgkin’s lymphoma, kidney transplantation from donors with HIV, a modular communicative leadless pacing–defibrillator system, stereotactic body radiotherapy in prostate cancer, and on how DNA sensing drives inflammation; a review article on cryoglobulinemia; a case report of a woman with dyspnea, dysphag…
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The Pulse of Progress: AI in Cardiology with Dr. David Ouyang
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50:23
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In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. David Ouyang, a cardiologist and AI researcher at Cedars-Sinai Medical Center. The conversation explores Ouyang’s journey from medical training to AI research and entrepreneurship, his groundbreaking work in applying AI to cardiology imaging, and the challenges of…
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NEJM Interview: Jean Nachega on the mpox Public Health Emergency of International Concern.
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9:20
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Jean Nachega is an associate professor of infectious diseases and microbiology and of epidemiology at the University of Pittsburgh School of Public Health and a professor of medicine at Stellenbosch University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J.B. Nachega and Others. Mpox in Pregnancy — Risks, Ve…
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Featuring articles on beta-blocker use after myocardial infarction and treatments for cerebral adrenoleukodystrophy and for small-cell lung cancer; a review article on hairy-cell leukemia; a case report of a man with fever, myalgia, jaundice, and respiratory failure; and Perspectives on Mpox, on addressing health care cost growth, and on confirmato…
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NEJM Interview: Jonathan Oberlander on the implications of the 2024 U.S. elections for health care reform.
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8:47
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Jonathan Oberlander is a professor of social medicine and of health policy and management at the University of North Carolina at Chapel Hill. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J. Oberlander. Health Care Reform and the 2024 U.S. Elections — Low Visibility, High Stakes. N Engl J Med 2024;391:1169-117…
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Featuring articles on lenacapavir for HIV prevention in cisgender women, tirzepatide for treatment of obstructive sleep apnea, lymphadenectomy for muscle-invasive bladder cancer, secondary T-cell lymphoma after CAR T-cell therapy, and immunity and early colorectal carcinogenesis; a review article on prolonged grief disorder; a Clinical Problem-Solv…
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