Neurosalience #S4E12 With Gang Chen - Statistician On Mission To Reduce FMRI Information Waste OHBM Neurosalience podcast

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S4, E1 - Day One 7:38

for 6 weeks siden7:38

7:38

Last summer, something monumental happened. One of Uncuffed's founding producers, Greg Eskridge, came home after more than 30 years in prison. In this episode we’ll bring you back to that emotional day last summer when he walked out of the San Quentin gates, free at last. Our work in prisons is supported by the California Arts Council, the California Department of Corrections and Rehabilitation, independent foundations, and donations from listeners like you. Learn more, sign up for Uncuffed news, and support the program at www.weareuncuffed.org Follow us @WeAreUncuffed on Instagram and Facebook Transcripts are available within a week of the episode coming out at www.kalw.org/podcast/uncuffed…

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Neurosalience #S4E12 with Gang Chen - Statistician on mission to reduce fMRI information waste

for ca. et år siden 1:13:58

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Indhold leveret af OHBM. Alt podcastindhold inklusive episoder, grafik og podcastbeskrivelser uploades og leveres direkte af OHBM eller deres podcastplatformspartner. Hvis du mener, at nogen bruger dit ophavsretligt beskyttede værk uden din tilladelse, kan du følge processen beskrevet her https://da.player.fm/legal.

Today, we are excited to have Dr. Gang Chen on the podcast. Dr. Chen is the go-to statistics guru for the fMRI community at the NIH and a well-respected scientist worldwide. He is a staff scientist in the group that developed the AFNI software package. As an applied mathematician, Dr. Chen has written a series of insightful papers in the past seven years, bucking the status quo in fMRI processing - essentially saying that we are throwing away too much valuable information by thresholding our data, relying on overly simple and rigid models of the hemodynamic response, not mapping effect sizes, and using center of mass measures to describe clusters of activation. He backs it all up with a rigorous approach characterized by all good statisticians. He is a master in the art of casting a wide net to capture useful data without taking in artifact and noise, finding that sweet spot in data reduction to balance utility with sensitivity.

In this episode, we hear all about Dr. Chen’s perspectives through these papers, which are so important yet not widely known or embraced by the field. We hope you enjoy it!

Episode producers:

Omer Faruk Gulban

Xuqian Michelle Li

… continue reading

102 episoder

#Science #Biology #OHBM

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Neurosalience #S4E12 with Gang Chen - Statistician on mission to reduce fMRI information waste

OHBM Neurosalience

16 subscribers

published for ca. et år siden

Del

MP3•Episode hjem

Indhold leveret af OHBM. Alt podcastindhold inklusive episoder, grafik og podcastbeskrivelser uploades og leveres direkte af OHBM eller deres podcastplatformspartner. Hvis du mener, at nogen bruger dit ophavsretligt beskyttede værk uden din tilladelse, kan du følge processen beskrevet her https://da.player.fm/legal.

Today, we are excited to have Dr. Gang Chen on the podcast. Dr. Chen is the go-to statistics guru for the fMRI community at the NIH and a well-respected scientist worldwide. He is a staff scientist in the group that developed the AFNI software package. As an applied mathematician, Dr. Chen has written a series of insightful papers in the past seven years, bucking the status quo in fMRI processing - essentially saying that we are throwing away too much valuable information by thresholding our data, relying on overly simple and rigid models of the hemodynamic response, not mapping effect sizes, and using center of mass measures to describe clusters of activation. He backs it all up with a rigorous approach characterized by all good statisticians. He is a master in the art of casting a wide net to capture useful data without taking in artifact and noise, finding that sweet spot in data reduction to balance utility with sensitivity.

In this episode, we hear all about Dr. Chen’s perspectives through these papers, which are so important yet not widely known or embraced by the field. We hope you enjoy it!

Episode producers:

Omer Faruk Gulban

Xuqian Michelle Li

… continue reading

102 episoder

#Science #Biology #OHBM

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Neurosalience #S5E10 with Simon Eickhoff - From Big Data to Biomarkers 1:19:38

for 8 dage siden1:19:38

1:19:38

In this episode of the OHBM Neurosalience Podcast, host Peter Bandettini sits down with Dr. Simon Eickhoff, a leading clinician-scientist in brain mapping. As a panelist at the 2024 OHBM meeting in Seoul, Dr. Eickhoff brought fascinating insights—this conversation picks up where that discussion left off.Dr. Eickhoff, a professor and director at Heinrich-Heine University Düsseldorf and Forschungszentrum Jülich, works at the crossroads of neuroanatomy, data science, and brain medicine. His research focuses on understanding individual differences in brain organization, aging, and psychiatric disorders using machine learning and large-scale neuroimaging analysis.Topics include: - The challenges of deriving biomarkers and using fMRI in clinical settings - His experience leading the journal Human Brain Mapping & the evolving publishing landscape - The role of AI in psychiatry and the future of precision medicineJoin us for a deep dive into the innovations and challenges shaping neuroscience and brain imaging today! Episode Producers Xuqian Michelle LiOmer Faruk Gulban…

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Neurosalience #S5E9 with Sepideh Sadaghiani - Brain network configurations using EEG and fMRI 1:24:35

for 23 dage siden1:24:35

1:24:35

This episode features Dr. Sepideh Sadaghiani directing the CONNECTlab at Beckman Institute for Advanced Science & Technology, University of Illinois at Urbana-Champaign. Dr. Sadaghiani’s lab explores large-scale brain networks, focusing on cognitive control, attention, and spontaneous neural activity. Using fMRI, EEG, and genetics, they uncover how brain connectivity shapes perception and behavior. Tune in for cutting-edge insights into the brain’s dynamic communication. Episode Producers Omer Faruk Gulban Karthik Sama…

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Neurosalience #S5E8 with Mac Shine - Focusing on the nexus of subcortex-cortex interactions 1:19:07

for 5 weeks siden1:19:07

1:19:07

This episode features Prof. Mac Shine from the University of Sydney. Mac is a systems neurobiologist interested in understanding how neurobiology supports awareness and flexible, parallel behavior. This engaging conversation between Peter and Mac offers takeaways for neuroscience from the study of other complex systems, such as weather patterns. It further explores how principles from fluid dynamics could inspire ways to rethink brain states and interpret fMRI data. The discussion also highlights the inherently interdisciplinary nature of neuroscience and emphasizes the crucial role of communication between its subfields as the field navigates these exciting times. For more details check out the episode! We hope you enjoy it! Episode Producers Alfie Wearn Karthik Sama…

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Neurosalience #S5E7 with Seiji Ogawa - The discoverer of the BOLD contrast and fMRI 1:09:11

for 7 weeks siden1:09:11

1:09:11

Join Peter Bandettini as he sits down with Seiji Ogawa, the visionary scientist behind the discovery of BOLD (blood oxygenation level-dependent) contrast fMRI. In this insightful conversation, Dr. Ogawa reflects on his groundbreaking work, the evolution of neuroimaging, and the challenges of translating fMRI into clinical practice. 1. Ogawa’s Early Journey – From Stanford to Bell Labs, and the influences that shaped his career. 2. The Discovery of BOLD fMRI – How experiments with hemoglobin oxygenation laid the foundation for modern neuroimaging. 3. Impact on Neuroscience – Why fMRI became a cornerstone in understanding brain function. 4. Challenges in Clinical Translation – Variability and reliability in single-subject analyses. 5. Scientific Reflections – Ogawa’s thoughts on curiosity, persistence, and the art of discovery. 6. Future Directions – Exploring brain interactions, neurovascular coupling, and innovations in imaging techniques. Notable Quotes: “If you can look into your brain without opening your skull… that’s a great thing.” “The important thing is to know what is important.” “Many phenomena don’t last long, but fMRI has proven to be enduringly significant.” Seiji Ogawa’s contributions have left an indelible mark on neuroscience, inspiring researchers worldwide. Don’t miss this fascinating exploration of his life, work, and ongoing curiosity about the mysteries of the human brain. Episode Producers Omer Faruk Gulban Nagashree Thovinakere…

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Neurosalience #S5E6 with Vesa Kiviniemi - Pulsations Matter: Imaging Glymphatic System using MREG 1:31:23

for 9 weeks siden1:31:23

1:31:23

Our guest today is Dr. Vesa Kiviniemi, a radiologist and researcher at Oulu University in Finland. Dr. Kiviniemi’s recent focus has been on using an extremely high-speed MRI technique called MREG. This technique allows for the collection of an entire volume of data with a TR of just 100 milliseconds, using a stack-of-spirals approach. The reason he values this technique so much is that it enables him to examine various types of brain pulsations, including cardiac and respiratory pulsations, as well as what he refers to as glymphatic or CSF pulsations. In this episode, Dr. Kiviniemi explores how he has applied this technique in his research. He also discusses the history of our understanding of the glymphatic system, its potential functions, the many unknowns surrounding it, and the opportunities it presents for future research. Among other topics, he explains why using this high-speed technique might complement—or in some cases even be better than—slower approaches in certain ways. We hope you enjoy the conversation! Episode producers: Xuqian Michelle Li Omer Faruk Gulban…

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Neurosalience #S5E5 with Peter Bandettini - The unique role of podcasts in communicating science 35:07

for 11 weeks siden35:07

35:07

This episode is unique in the sense that it’s actually a talk Peter gave during the OHBM 2024 meeting, specifically during the education session on communicating science. Peter wanted to share this talk because it focuses on the podcast and his own approach to creating it. He discusses his philosophy, heuristics, what he considers important about podcasting, and why he enjoys doing it. The talk emphasizes the value of conversation and explains how the podcast showcases the human side of scientific investigators and the stories behind their research. We hope you enjoy it! Episode producers: Omer Faruk Gulban Xuqian Michelle Li…

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Neurosalience #S5E4 with Matthew Cobb - The idea of the brain, Francis Crick, and consciousness 1:31:49

for 13 weeks siden1:31:49

1:31:49

In this episode, Peter Bandettini interviews Matthew Cobb (https://en.wikipedia.org/wiki/Matthew_Cobb), the author of the book “The idea of the brain: The Past and Future of Neuroscience”. Episode producers: Omer Faruk Gulban Alfie Wearn

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Neurosalience #S5E3 with Alan Evans - 40 years of brain imaging & creating infrastructure for all 1:24:26

for 15 weeks siden1:24:26

1:24:26

Our guest is today is Dr. Alan Evans. He completed his Ph.D. (1979) and post-doctoral fellowship studying structure-function interaction of proteins at the Department of Biophysics at Leeds University in the U.K. Subsequently he worked for five years as a PET physicist at Atomic Energy of Canada in Ottawa. In 1984, he joined the Department of Neurology and Neurosurgery at McGill University, where his research interests include multimodal brain imaging with PET and MRI, structural network modelling, and large scale neural informatics. For the past 40 years, he has been an institution at McGill University. He is the co-director of the Ludmer Centre and He is currently Co-Director of both the Ludmer Centre for Neuroinformatics and Mental Health and the Helmholtz International BigBrain Analytics Learning Laboratory (HIBBALL). He is Scientific Director of McGill’s “Healthy Brains, Healthy Lives” (HBHL) , and Scientific Director of the Canadian Open Neuroscience Platform (CONP). The technical infrastructure underpinning CONP includes a multi-modal databasing system (LORIS) and an international grid-processing portal (CBRAIN) both developed in Prof. Evan’s MCIN lab. These platforms also support international brain networks, notably the Canada-China-Cuba Axis and the Global Brain Consortium, both co-chaired by Prof. Evans. Furthermore, he was named the Victor Dahdaleh Chair in Neurosciences in October of 2022. Episode producers Xugian Michelle Li Nagashree Thovinakere…

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Neurosalience #S5E2 with Angela Laird - Forging the meta-analysis movement in neuroimaging 1:09:55

for 17 weeks siden1:09:55

1:09:55

Today our guest is Dr. Angie Laird, who trained as an imaging physicist, but has evolved into a cognitive neuroscientist and a true pioneer in meta-analysis of fMRI data. Dr. Laird has spent the bulk of her career developing novel data analysis algorithms, neuroscience informatics tools, and neuroimaging ontologies to yield analytic strategies for improving investigations into functional brain networks of healthy individuals as well as in populations with psychiatric and neurologic diseases and disorders. Early on she has seen the untapped value in meta-analysis, and has fostered growth in this fundamentally important area in functional brain imaging. Dr. Laird received her B.S. in Physics from Florida State University in 1998, and her Ph.D. in Medical Physics from the University of Wisconsin-Madison in 2002. She was a faculty member at the Research Imaging Institute of the University of Texas Health Science Center in San Antonio from 2004-2012, and currently she is Professor and Director for Imaging Science at Florida International University in Miami. Along with her development of meta-analysis tools and her own research, she plays a central role in the Adolescent Brain Cognitive Development (ABCD) consortium which is the largest long-term study of brain development and child health in the United States. This was a great conversation that spanned the early culture of fMRI research, early efforts towards data sharing, to the current practices today where data sharing and analyzing data across studies and from large shared datasets is becoming the norm. We also spent time talking about the origin, logistics, and impact of the ABCD project. We hope you enjoy it! Episode producers: Omer Faruk Gulban Xuqian Michelle Li…

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Neurosalience #S5E1 - Highlights of the last season and more 44:52

for 19 weeks siden44:52

44:52

In this special kickoff to the new season of Neurosalience , we turn the tables as Peter Bandettini, our host, joins us as the guest! We dive into highlights from last season and explore exciting plans for the episodes ahead. In addition, we had an insightful conversation on resting-state fMRI, computational modeling of the brain, and the importance of deep sampling in individuals. Plus, we discuss some news on the shifting landscape of scientific publishing. We hope that you enjoy the new season of Neurosalience. Episode producers: Omer Faruk Gulban…

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Neurosalience #S4E21 [Season Final] - OHBM 2024 Live Podcast 1:34:16

for 36 weeks siden1:34:16

1:34:16

In this final episode of Neurosalience Season 4, Peter Bandettini hosts Janaina Mourao-Miranda, Simon Eickhoff, Sepideh Sadaghiani, Thomas Yeo, Michael Milham. The discussion was centered around: Clinical relevance of fMRI today. Future directions of neuroimaging, promises to get excited about, and overpromises that need to be considered cautiously. How can fMRI help to understand the brain from a general point of view. This is the final episode of Neurosalience Season 4! See you in the next season :) Episode producers: Omer Faruk Gulban…

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Neurosalience #S4E20 with Polimeni J., Huber L., Stikov N., Vizioli L., Yacoub E. - OHBM vs ISMRM 1:13:47

for 39 weeks siden1:13:47

1:13:47

In this episode, Peter Bandettini hosts Jon Polimeni, Renzo Huber, Nikola Stikov, Luca Vizioli, and Essa Yacoub. They talk about the International Society for Magnetic Resonance in Medicine (ISMRM) and Organization for Human Brain Mapping (OHBM) conferences where they have attended both over many years. The conversation revolves around what each meeting offers, how they differ, how we might increase cross-talk, and why that would be a good thing. They also highlight some of the exciting work and developments gleaned from ISMRM that might not appear at OHBM. Enjoy! Episode producers: Omer Faruk Gulban…

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Neurosalience #S4E19 with Sofie Valk, Hae-Jeong Park, Kevin Sitek - OHBM 2024 Preview 1:05:43

for 39 weeks siden1:05:43

1:05:43

Here Kevin Sitek (the Chair of the OHBM Communications Committee and a Research Assistant Professor in Communication Sciences and Disorders at Northwestern University), Sofie Valk (Research group leader and Scientific representative at Otto Hahn Group Cognitive Neurogenetics), and Hae-Jeong Park (Professor of Nuclear Medicine, Yonsei University College of Medicine, South Korea) discuss what to expect from OHBM 2024, including the education sessions, Oral Sessions, Symposia, Keynotes, and Talairach Lecture as well as discussion of the many informal round table sessions offered, the social events, the outreach, the SIGs, and the Communication Committee. They also discussed a bit about Korea and how the meeting came to be here this year. A great discussion with lots of information! See you there June 23 to June 27! Episode producers: Omer Faruk Gulban Xuqian Michelle Li…

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Neurosalience #S4E18 with Vince Calhoun - (Part 2/2) A principled approach to data mining 1:09:42

for 40 weeks siden1:09:42

1:09:42

Dr. Vince Calhoun is the founding director of the tri-institutional center for translational research in Neuroimaging and Data Science (TReNDS) which is a consortium formed by Georgia State University, Georgia Tech, and Emory University. In this part 2 of Peter and Vince’s discussion, they dive further into addressing the challenges that fMRI and other modalities face in finding useful information about psychiatric disorders that can be used clinically. They talk about what neuroimaging has taught us about schizophrenia, as well as the goals and challenges of establishing clinical relevance. They also talk a bit about the importance of a data driven approach to development of processing methods, as well as variability in fMRI data, and the challenges and opportunities that big data sets offer, the promise of data fusion, and multivariate modeling. Lastly, they also discuss his latest work in deep learning and what it offers, and spend quite a bit of time discussing data driven approaches vs model driven approaches. This discussion was an outstanding perspective builder. We hope that you enjoy it! Episode producers: Omer Faruk Gulban Xuqian Michelle Li…

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OHBM2024 Keynote Interview Nicola Palomero-Gallagher 33:48

for 41 weeks siden33:48

33:48

#A conversation with 2024 Keynote Speaker Nicola Palomero-Gallagher TODO: Link to blog post Interviewers: - Naomi L. Gaggi - Beatriz Padrela

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